SUCCEED® Veterinary Formula

What solution do you have for poor GI health in your clients’ horses?

You know that many of your clients’ horses are struggling with poor digestive health brought on by management practices and the rigors of breeding, training and competition. You may have tested with the SUCCEED Equine Fecal Blood Test and gotten positive results indicating GI conditions. But what tool do you have in your arsenal for supporting equine digestive health in the face of the myriad of issues that challenge it?

Provide optimal GI health for horses and good business for your practice.

With SUCCEED Veterinary Formula, you get a trusted, natural approach to supporting GI health—plus a consistent, growing revenue stream for your practice. To keep your client’s horses healthy, maintain optimal gastrointestinal health with the one digestive product that is:

  • Patented—validated with multiple patents in the U.S. and worldwide.
  • Tested—evaluated in various clinical trials.
  • Supported—includes the industry’s best colic reimbursement program.

An Exclusive Product for Veterinarians

SUCCEED Veterinary Formula (VF) provides advanced support for the entire equine gastrointestinal tract using a natural, nutritional approach. Sold exclusively through veterinarians, SUCCEED VF builds on the foundation of the original SUCCEED formula with added amino acids to further support mucus production, healthy development of enterocytes and the biosynthesis of proteins that aid healthy muscle tone. And as a nutritional product, it does not test in competition horses.

With daily use, SUCCEED VF can help maintain the optimal GI health of your clients’ horses while generating a steady revenue stream for your practice.

Licensed for sale in the United States only.

SDCPVF carton NEW 2017 rev4-no-shadow
VF logo and text-crop

Veterinary Colic Reimbursement Program

Pays for colic treatment for any horse continuously on SUCCEED VF.

  • Up to $800 for medical colic care.
  • Up to $15,000 for colic surgery.
  • Horse must be on SUCCEED VF for at least 90 days.
  • Excludes colic unrelated to GI dysfunction.
  • Payments are made direct to you, the vet.

The Healthy Gut Commitment

Reimbursement Terms

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SUCCEED® Means Science

From the very beginning, SUCCEED has been developed on a strong foundation of science and research and supported with extensive trials to test performance and clinical value.

A Comparison Between Omeprazole and a Dietary Supplement for the Management of Squamous Ulceration in Horses

Journal of Equine Veterinary Science, May 2016

Ingredients in SUCCEED® Veterinary Formula

Click on an ingredient to learn more.

Oat Oil
(rich in polar lipids)

Oat Oil (rich in polar lipids)

Oat oil is rich in polar lipids, particularly galactolipids. Dietary polar lipids are important in forming the tight junctions between the epithelial cells lining the gut.

Oat oil is also rich in trienols and tocopherols, powerful antioxidants that sweep free radicals out of the system before they can damage the surrounding tissue.

Polar lipids are versatile emulsifiers, stabilizing oil-water mixtures. As such, they provide an ideal nutrient delivery vehicle, capable of transferring both fat- and water-soluble molecules into the tissues. Adding polar lipids to the diet has been shown to protect the intestinal mucosa and to strengthen the impermeability of the barrier.

All of this works together to enhance the equine GI tract’s natural protection from acids and ability to absorb nutrients fully, while safely removing potentially harmful pathogens from the hindgut.

Oat Flour
(rich in beta glucan)

Oat Flour (rich in beta glucan)

Beta-glucan is a polysaccharide derived from yeast, barley and oats. It has been known for years to reduce LDL cholesterol levels in the blood. More significantly, beta-glucan serves an important role as a potent immuno-stimulator. It induces macrophages, which have a specific beta-glucan receptor, to mount a full-blown immune system response to pathogenic microbes. This aids in healing damaged tissue in the horse’s hindgut.

Beta-glucan also creates a gel in aqueous solutions, slowing the transit of digesta through the gut. This allows starches to be digested earlier in the system, thereby reducing the negative effects of starch in the hind gut.

Finally, beta-glucan moderates the release of sugars from the digestive system, helping to prevent the sugar highs and lows that often afflict animals that are fed only two or three times a day on an energy-rich high carbohydrate diet.

Altogether, beta-glucan is highly beneficial for both healing and the protection of the hindgut.

Yeast Products

Yeast Products

Nucleotides

The cells of the intestinal mucosa are constantly dividing, ultimately managing to totally replace the digestive tract lining about every three days. This continuous cell division requires the replication of millions of DNA molecules every second. In turn, each DNA molecule is made up of several billion nucleotides. This represents a sizeable expenditure of energy-intensive chemical synthesis. Maintaining an adequate level of nucleotides is thus a major, ongoing issue for the digestive system.

Studies have demonstrated that nucleotide supplements increase mucosal thickness and protein levels and may also speed up intestinal recovery after chronic diarrhea and intestinal damage.

Dietary nucleotides also seem to have an important beneficial effect on the intestinal microflora, stimulating the growth of beneficial bacteria and inhibiting pathogens.

Mannan Oligosaccharides

Extracts of yeast (saccharomyces cerevisiae) have been found to bind pathogens, perhaps because their mannan oligosaccharide (MOS) content mimics the carbohydrates in the enterocyte membranes. Pathogens mistakenly bind with MOS instead of the enterocytes, and are subsequently flushed out of the digestive system. Along with the pathogens go the toxins they would have produced.

MOS can be digested by the enzymes of certain beneficial bacteria. So, in addition to discouraging pathogenic bacteria, MOS also promotes the growth of beneficial microbes such as lactobacillus.

MOS also stimulates the immune system and encourages the growth of intestinal villi, showing improved digestion and absorption of nutrients in various animal studies.

Amino Acids

Amino Acids

Glutamine

Glutamine is the most abundant amino acid in humans as well as horses. Glutamine deficits can result in diarrhea, villous atrophy, mucosal ulceration, increased intestinal permeability and necrosis.

Glutamine is a muscle fuel and also supplies nitrogen to the immune cells of the intestinal mucosa, which help to prevent pathogenic organisms from entering the circulatory system.

Glutamine can be administered parenterally to animals recovering from abdominal surgery to reduce healing time.

Glutamine is considered to be a nonessential amino acid under normal conditions, because the body can create as much as is needed de novo. But Glutamine is also known to be “conditionally essential.” During periods of metabolic or digestive stress such as ulceration or malnutrition, large amounts of glutamine are consumed, and supplements may be needed to replenish the supply. The intestines, along with immune and kidney cells, are the primary consumers of glutamine in animals.

Threonine, Proline and Serine

Threonine contributes to a smoothly functioning GI tract by assisting metabolism and nutrient absorption. A deficiency of threonine slows the regeneration of the gut wall and depresses the production of mucus. Threonine is especially useful for wound healing and for treating stress. It is also an essential link in the production of immunoglobulins.

Threonine, proline and serine are the three most important amino acids in the mucus proteins that, along with sugars, make up mucus. Together, they account for over 40% of the total amino acids found in mucus.

A continuous layer of mucus protects the lining of the gut and is produced by goblet cells distributed throughout the intestinal tract. However, bacteria and toxins can disrupt this mucus layer and damage the enterocytes lining the GI tract, leading to lesions and inflammation. In cases of ulcerative colitis, the mucus layer is denuded in the areas of greatest inflammation. In order to maintain uninterrupted protection, extra mucus needs to be secreted. In times of stress, extra amino acids in the diet can be scavenged to help create new mucus quickly.

A specific mix of threonine, proline and serine has been shown to be beneficial in studies where dextran sulfate sodium was used to induce a model of ulcerative colitis. The extra amino acids increased the number of mucus-producing goblet cells at the ulcer sites. In addition, an optimal ratio of the three amino acids restored the gut microbiota to pre-treatment values. We have reproduced the relative proportions of this restorative amino acid triplet in this formula.

Leucine

Leucine increases the post-feeding insulin response in horses. Both before and after exercise, leucine augments the rate of muscle glycogen synthesis. Glycogen provides energy storage for muscles, including the muscles encasing the gut. Glycogen is always observed in the stratified epithelium of mucus membranes. In addition, leucine is lost due to oxidation in the presence of trichostrongylus colubriformis (strongyles), leading to reduced growth rates.

Isoleucine

Serum isoleucine, along with leucine, is depleted after exercise and can take 48 hours to recover. Isoleucine is a component of peptide histidine isoleucine (PHI), which is found throughout the digestive system, but particularly in the colon. PHI, in turn, plays a role in the regulation of the immune system through its interplay with prolactin.

Lysine

Lysine is an essential amino acid that has a major role in building muscle protein, in recovery from injury and is important to the growth of horses, especially yearlings. Lysine and proline are important to GI healing and the formation of collagen.

Downloads

SUCCEED VF and Healthy Gut Commitment Program Flyer

Download to read and print detailed product information for yourself and your clients.

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SUCCEED Veterinary Formula Product Label

Review the package and labeling for SUCCEED Veterinary Formula.

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SUCCEED VF Information and Research

Detailed information on the ingredients, research, and testing behind SUCCEED Veterinary Formula.

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Instructions for Use

Applications

Use daily for horses in situations where environment and care may adversely affect digestive health, such as:

  • For horses kept in stalls, fed intermittently on high grain diets, or facing the challenges of training and competition.
  • For mares during pregnancy and foals during weaning.
  • As part of a regular wellness program.

Administration

Feed SUCCEED twice each day for first week of use, once each day thereafter.

  • Paste – Empty contents of one tube (26.5 grams) on top of horse’s feed.
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Purchase SUCCEED® VF from Your Veterinary Supply Distributor

U.S. Vet Supply Distributors

Research & Education

Independent Research Freedom Health Research Equine GI Disease Library

Vet Center Blog:

GI health and management discussion, research and product news.

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Managing GI Health to Reduce Risk of Enteritis

While gastric ulcers are a common focus in equine practice, intestinal pathologies found beyond the stomach may present a greater challenge for veterinarians. Enteritis and other intestinal disorders can be difficult to diagnose. But these […]

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Hindgut Significance and Pathologies in Performance Horses

Equine veterinarians are starting to recognize the importance of the hindgut in digestive wellness as well as the problems that affect it. Hindgut health is vital to a horse’s overall health and performance, and it […]

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Strategies for Supporting GI Health in the Surgical Horse

Maintaining a healthy GI tract via nutritive support is key to effective surgery preparation and rapid post-op recovery in horses. Impaired GI health is directly associated with impaired immune health (Schley and Field, 2002; Artis, […]

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The Cycle of Performance and Malnutrition in Horses

When it comes to a horse’s health, nothing is more important than nutrition. It plays a role in almost everything—weight, body condition, attitude, energy, immunity, hoof health, and even mental focus. Therefore, appropriate and adequate […]

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The Relationship Between Stereotypies and Microbes

Stereotypies, such as cribbing and stall-walking, are not found in wild horses, thus are likely a direct result of domestication and modern husbandry practices. While they may arise for a variety of reasons, these vices […]

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Early Detection & Accurate Diagnosis of Equine Hindgut Pathologies

When it comes to the gastrointestinal health of our patients, equine veterinarians are highly aware of the widespread nature of gastric ulceration, especially for horses used in competition and professional settings. We also deal with […]

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